Introduces students to machine learning in healthcare, including the nature of clinical data and the use of machine learning for risk stratification, disease progression modeling, precision medicine, diagnosis, subtype discovery, and improving clinical workflows. Topics include causality, interpretability, algorithmic fairness, time-series analysis, graphical models, deep learning and transfer learning. Guest lectures by clinicians from the Boston area and course projects with real clinical data emphasize subtleties of working with clinical data and translating machine learning into clinical practice.
This quiz will not count toward your grade, but will be used by the course staff to check prerequisites (6.036/6.862 or 6.867 or 9.520/6.860 or 6.806/6.864 or 6.438 or 6.034) and to assess students' preparation for this class.
You can take the prerequisite quiz here. If you intend to take this class, you must take this quiz before 11:59 p.m. EST on Tuesday, February 4th, 2020
Schedule is subject to change.
Class | Date | Lecture Materials | Assignments |
---|---|---|---|
1 | Tuesday Feb 04 |
Introduction: What makes healthcare unique?
|
|
2 | Thursday Feb 06 |
Overview of Clinical Care
|
|
3 | Tuesday Feb 11 |
Deep Dive into Clinical Data
|
|
4 | Thursday Feb 13 |
Risk Stratification
|
|
Friday Feb 14 - Recitation on querying MIMIC with SQL to recreate Lecture 3 slides | |||
Tuesday Feb 18 | Monday Schedule - No Class |
||
5 | Thursday Feb 20 |
Learning with Noisy and Censored Labels
|
|
6 | Tuesday Feb 25 |
Clinical Natural Language Processing (NLP)
|
|
7 | Thursday Feb 27 |
Interpretability
|
|
Friday Feb 28 - Recitation primarily on contextual embeddings for medical disambiguation | |||
8 | Tuesday Mar 3 |
Learning to Defer & Uncertainty
|
|
9 | Thursday Mar 5 |
Small to big Data: Case Studies with Physiological Time-series
|
|
10 | Tuesday Mar 10 |
Detecting Dataset Shift
|
|
11 | Thursday Mar 12 |
Fairness
|
|
12 | Tuesday Mar 17 |
Cancelled due to COVID
|
|
13 | Thursday Mar 19 |
Cancelled due to COVID
|
|
Tuesday Mar 24 | Spring Vacation |
||
Thursday Mar 26 | Spring Vacation |
||
14 | Tuesday Mar 31 |
Causal Inference: Potential Outcomes, Regression
|
|
15 | Thursday Apr 2 |
Causal Inference: Inverse Propensity Reweighting
|
|
16 | Tuesday Apr 7 |
Off-policy Reinforcement Learning
|
|
17 | Thursday Apr 9 |
Guest Lecture: David Bates, Harvard Medical School
|
|
18 | Tuesday Apr 14 | Guest Lecture: Andrew Beck, PathAI
|
|
Thursday Apr 16 |
No Class - QUIZ
|
||
19 | Tuesday Apr 21 |
Precision Medicine
|
|
20 | Thursday Apr 23 |
Disease Progression & Subtyping Pt. 1
|
|
21 | Tuesday Apr 28 |
Disease Progression & Subtyping Pt. 2
|
|
Thursday Apr 30 |
Project Discussions
|
||
22 | Tuesday May 5 |
Differential Diagnosis
|
|
23 | Thursday May 7 |
Automating Clinical Workflows
|
|
Tuesday May 12 | Final Project Discussion and Poster Session |
In order to access sensitive healthcare datasets, you will need to complete several preliminary tasks. Please see here for full instructions and submission details.
Due to the switch to virtual classes, we have links to recent course videos available on Stellar here. These are only accessible to students enrolled in the course.
Scribing is one mandatory component of your participation grade. Scribing for a lecture will consist of taking high-quality, detailed notes during the lecture in question then working with your scribing team to compile a polished, electronic version of these notes under our direction.
Full instructions for scribing, including how to sign-up for particular scribe dates, can be found here. Please let us know via Piazza if you have any questions!
(starting for pset1 onwards)
Scenarios: